Ageing and neurotrophic signalling effects on diaphragm neuromuscular function

The age-related mechanisms underlying sarcopenia are largely unknown. We hypothesize that age-related neuromuscular changes depend on brain-derived neurotrophic factor (BDNF) acting through the tropomyosin-related kinase receptor B (TrkB). Maximal specific force and neuromuscular transmission failur...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Greising, Sarah M, Ermilov, Leonid G, Sieck, Gary C, Mantilla, Carlos B
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Respiratory
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303387/
https://ncbi.nlm.nih.gov/pubmed/25630263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.282244
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