Dominant role of interstitial cells of Cajal in nitrergic relaxation of murine lower oesophageal sphincter

Oesophageal achalasia is a disease known to result from reduced relaxation of the lower oesophageal sphincter (LES). Nitric oxide (NO) is one of the main inhibitory transmitters. NO-sensitive guanylyl cyclase (NO-GC) acts as the key target of NO and, by the generation of cGMP, mediates nitrergic rel...

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Dettagli Bibliografici
Pubblicato in:J Physiol
Autori principali: Groneberg, Dieter, Zizer, Eugen, Lies, Barbara, Seidler, Barbara, Saur, Dieter, Wagner, Martin, Friebe, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
Soggetti:
Alimentary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303385/
https://ncbi.nlm.nih.gov/pubmed/25630261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.273540
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