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Dominant role of interstitial cells of Cajal in nitrergic relaxation of murine lower oesophageal sphincter
Oesophageal achalasia is a disease known to result from reduced relaxation of the lower oesophageal sphincter (LES). Nitric oxide (NO) is one of the main inhibitory transmitters. NO-sensitive guanylyl cyclase (NO-GC) acts as the key target of NO and, by the generation of cGMP, mediates nitrergic rel...
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| Veröffentlicht in: | J Physiol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303385/ https://ncbi.nlm.nih.gov/pubmed/25630261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.273540 |
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