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X-ray Crystallographic Structure of BshC, a Unique Enzyme Involved in Bacillithiol Biosynthesis

[Image: see text] Bacillithiol is produced by many Gram-positive bacteria via a pathway utilizing the enzymes BshA, BshB, and BshC. Here we report the 1.77 Å resolution crystal structure of BshC, the putative cysteine ligase in bacillithiol production. The structure reveals that BshC contains a core...

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Publicat a:Biochemistry
Autors principals: VanDuinen, Andrew J., Winchell, Kelsey R., Keithly, Mary E., Cook, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303302/
https://ncbi.nlm.nih.gov/pubmed/25496067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501394q
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