Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver.
Cobalt has complex actions on the metabolism of heme in the liver. In this organ the metal potently induces heme oxygenase (EC 1.14.99.3), and decreases cellular heme and hemoprotein content. The metal also displays biphasic effects on hepatic heme synthesis. These effects are reflected in the abili...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1976
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/818637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.5.1499 |
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