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Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver.

Cobalt has complex actions on the metabolism of heme in the liver. In this organ the metal potently induces heme oxygenase (EC 1.14.99.3), and decreases cellular heme and hemoprotein content. The metal also displays biphasic effects on hepatic heme synthesis. These effects are reflected in the abili...

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Detalhes bibliográficos
Main Authors: Maines, M D, Janousĕk, V, Tomio, J M, Kappas, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430324/
https://ncbi.nlm.nih.gov/pubmed/818637
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