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Cobalt Induction of Hepatic Heme Oxygenase; with Evidence That Cytochrome P-450 Is Not Essential for This Enzyme Activity

Treatment of rats in vivo with cobalt chloride stimulated heme oxidation by hepatic microsomes to levels up to 800% above controls. This treatment also caused increases in liver weight and in total microsomal protein; in contrast, marked decreases were produced in microsomal oxidation of ethylmorphi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Maines, M. D., Kappas, Attallah
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530983/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4293
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