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Improved detection of artifactual viral minority variants in high-throughput sequencing data

High-throughput sequencing (HTS) of viral samples provides important information on the presence of viral minority variants. However, detection and accurate quantification is limited by the capacity to distinguish biological from artificial variation. In this study, errors related to the Illumina Hi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Welkers, Matthijs R. A., Jonges, Marcel, Jeeninga, Rienk E., Koopmans, Marion P. G., de Jong, Menno D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302989/
https://ncbi.nlm.nih.gov/pubmed/25657642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00804
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