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Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins

The capability to conditionally inactivate gene function is essential for understanding the molecular basis of development. In gene and mRNA targeting approaches, protein products can perdure, complicating genetic analysis. Current methods for selective protein degradation require drug treatment or...

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Dades bibliogràfiques
Publicat a:Development
Autors principals: Armenti, Stephen T., Lohmer, Lauren L., Sherwood, David R., Nance, Jeremy
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302935/
https://ncbi.nlm.nih.gov/pubmed/25377555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115048
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