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Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins

The capability to conditionally inactivate gene function is essential for understanding the molecular basis of development. In gene and mRNA targeting approaches, protein products can perdure, complicating genetic analysis. Current methods for selective protein degradation require drug treatment or...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Armenti, Stephen T., Lohmer, Lauren L., Sherwood, David R., Nance, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302935/
https://ncbi.nlm.nih.gov/pubmed/25377555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115048
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