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RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

Stem cells are influenced by their surrounding microenvironment, or niche. In the testis, Sertoli cells are the key niche cells directing the population size and differentiation fate of spermatogonial stem cells (SSCs). Failure to properly regulate SSCs leads to infertility or germ cell hyperplasia....

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Garcia, Thomas Xavier, Farmaha, Jaspreet Kaur, Kow, Sean, Hofmann, Marie-Claude
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302926/
https://ncbi.nlm.nih.gov/pubmed/25406395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113969
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