Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program

Nodal/TGFβ signaling regulates diverse biological responses. By combining RNA-seq on Foxh1 and Nodal signaling loss-of-function embryos with ChIP-seq of Foxh1 and Smad2/3, we report a comprehensive genome-wide interaction between Foxh1 and Smad2/3 in mediating Nodal signaling during vertebrate mesen...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Chiu, William T., Charney Le, Rebekah, Blitz, Ira L., Fish, Margaret B., Li, Yi, Biesinger, Jacob, Xie, Xiaohui, Cho, Ken W. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302925/
https://ncbi.nlm.nih.gov/pubmed/25359723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.107227
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