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SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)

Upon removal of culture conditions that maintain an undifferentiated state, mouse embryonic stem cells (ESCs) differentiate into various cell types. Differentiation can be facilitated by forced expression of certain transcription factors (TFs), each of which can generally specify a particular develo...

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Vydáno v:Development
Hlavní autoři: Yamamizu, Kohei, Schlessinger, David, Ko, Minoru S. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302912/
https://ncbi.nlm.nih.gov/pubmed/25371362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115436
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