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Making designer mutants in model organisms
Recent advances in the targeted modification of complex eukaryotic genomes have unlocked a new era of genome engineering. From the pioneering work using zinc-finger nucleases (ZFNs), to the advent of the versatile and specific TALEN systems, and most recently the highly accessible CRISPR/Cas9 system...
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| Publicado no: | Development |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302887/ https://ncbi.nlm.nih.gov/pubmed/25336735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.102186 |
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