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Compounds with species and cell type specific toxicity identified in a 2,000 compound drug screen of neural stem cells and rat mixed cortical neurons

Human primary neural tissue is a vital component for the quick and simple determination of chemical compound neurotoxicity in vitro. In particular, such tissue would be ideal for high-throughput screens that can be used to identify novel neurotoxic or neurotherapeutic compounds. We have previously e...

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Vydáno v:Neurotoxicology
Hlavní autoři: Malik, Nasir, Efthymiou, Anastasia G., Mather, Karly, Chester, Nathaniel, Wang, Xiantao, Nath, Avindra, Rao, Mahendra S., Steiner, Joseph P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302729/
https://ncbi.nlm.nih.gov/pubmed/25454721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2014.10.007
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