Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System

There is great need to develop more predictive drug discovery tools to identify new therapies to treat diseases of the central nervous system (CNS). Current nonpluripotent stem cell-based models often utilize non-CNS immortalized cell lines and do not enable the development of personalized models of...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Dev
Autori principali: Hunsberger, Joshua G., Efthymiou, Anastasia G., Malik, Nasir, Behl, Mamta, Mead, Ivy L., Zeng, Xianmin, Simeonov, Anton, Rao, Mahendra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
Soggetti:
Comprehensive Reviews
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533087/
https://ncbi.nlm.nih.gov/pubmed/25794298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0531
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