Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System

There is great need to develop more predictive drug discovery tools to identify new therapies to treat diseases of the central nervous system (CNS). Current nonpluripotent stem cell-based models often utilize non-CNS immortalized cell lines and do not enable the development of personalized models of...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Hunsberger, Joshua G., Efthymiou, Anastasia G., Malik, Nasir, Behl, Mamta, Mead, Ivy L., Zeng, Xianmin, Simeonov, Anton, Rao, Mahendra
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Comprehensive Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533087/
https://ncbi.nlm.nih.gov/pubmed/25794298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0531
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