Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4

BACKGROUND: Acquisition of the M1 or M2 phenotypes by microglia has been shown to occur during the development of pathological conditions, with M1 activation being widely involved in neurotoxicity in relation with the anatomical localization and the reactivity of subtypes of microglia cells. On the...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Pepe, Giovanna, Calderazzi, Giorgia, De Maglie, Marcella, Villa, Alessandro Maria, Vegeto, Elisabetta
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302702/
https://ncbi.nlm.nih.gov/pubmed/25551794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0211-6
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