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Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4

BACKGROUND: Acquisition of the M1 or M2 phenotypes by microglia has been shown to occur during the development of pathological conditions, with M1 activation being widely involved in neurotoxicity in relation with the anatomical localization and the reactivity of subtypes of microglia cells. On the...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Pepe, Giovanna, Calderazzi, Giorgia, De Maglie, Marcella, Villa, Alessandro Maria, Vegeto, Elisabetta
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302702/
https://ncbi.nlm.nih.gov/pubmed/25551794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0211-6
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