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Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4

BACKGROUND: Acquisition of the M1 or M2 phenotypes by microglia has been shown to occur during the development of pathological conditions, with M1 activation being widely involved in neurotoxicity in relation with the anatomical localization and the reactivity of subtypes of microglia cells. On the...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Pepe, Giovanna, Calderazzi, Giorgia, De Maglie, Marcella, Villa, Alessandro Maria, Vegeto, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302702/
https://ncbi.nlm.nih.gov/pubmed/25551794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0211-6
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