Hyperuricemia and urate nephropathy in urate oxidase-deficient mice.

Urate oxidase, or uricase (EC 1.7.3.3), is a purine metabolic enzyme that catalyzes the conversion of uric acid to allantoin in most mammals except humans and certain other primates. The loss of urate oxidase in the human during primate evolution predisposes man to hyperuricemia, a metabolic disturb...

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Bibliografiske detaljer
Main Authors: Wu, X, Wakamiya, M, Vaishnav, S, Geske, R, Montgomery, C, Jones, P, Bradley, A, Caskey, C T
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43025/
https://ncbi.nlm.nih.gov/pubmed/8290593
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