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Direct experimental evidence for kinetic proofreading in amino acylation of tRNAIle.

Kinetic proofreading is a reaction scheme with a structure more complicated than that of Michaelis kinetics, which leads to a proofreading for errors in the recognition of a correct substrate by an enzyme. We have measured the stoichiometry between ATP hydrolysis and tRNAIle charging, using the enzy...

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Detalhes bibliográficos
Main Authors: Hopfield, J J, Yamane, T, Yue, V, Coutts, S M
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430221/
https://ncbi.nlm.nih.gov/pubmed/1063397
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