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Direct experimental evidence for kinetic proofreading in amino acylation of tRNAIle.
Kinetic proofreading is a reaction scheme with a structure more complicated than that of Michaelis kinetics, which leads to a proofreading for errors in the recognition of a correct substrate by an enzyme. We have measured the stoichiometry between ATP hydrolysis and tRNAIle charging, using the enzy...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1976
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430221/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1063397/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.4.1164 |
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