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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions. Small replicate numbers, discreteness, large dynamic range and the presence of outliers requ...
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| Publicado en: | Genome Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302049/ https://ncbi.nlm.nih.gov/pubmed/25516281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0550-8 |
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