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A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data

Recent developments in RNA-sequencing (RNA-seq) technology have led to a rapid increase in gene expression data in the form of counts. RNA-seq can be used for a variety of applications, however, identifying differential expression (DE) remains a key task in functional genomics. There have been a num...

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Detalhes bibliográficos
Main Authors: Wu, Hao, Wang, Chi, Wu, Zhijin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590927/
https://ncbi.nlm.nih.gov/pubmed/23001152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs033
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