Mitochondrial Remodeling in Mice with Cardiomyocyte-Specific Lipid Overload

BACKGROUND: Obesity leads to metabolic heart disease (MHD) that is associated with a pathologic increase in myocardial fatty acid (FA) uptake and impairment of mitochondrial function. The mechanism of mitochondrial dysfunction in MHD, which results in oxidant production and decreased energetics, is...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Elezaby, Aly, Sverdlov, Aaron L., Tu, Vivian H., Soni, Kanupriya, Luptak, Ivan, Qin, Fuzhong, Liesa, Marc, Shirihai, Orian S., Rimer, Jamie, Schaffer, Jean E., Colucci, Wilson S., Miller, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301992/
https://ncbi.nlm.nih.gov/pubmed/25497302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.12.001
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