High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II

BACKGROUND: Diet-induced obesity leads to metabolic heart disease (MHD) characterized by increased oxidative stress that may cause oxidative post-translational modifications (OPTM) of cardiac mitochondrial proteins. The functional consequences of OPTM of cardiac mitochondrial proteins in MHD are unk...

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Udgivet i:J Mol Cell Cardiol
Main Authors: Sverdlov, Aaron L., Elezaby, Aly, Behring, Jessica B., Bachschmid, Markus M., Luptak, Ivan, Tu, Vivian H., Siwik, Deborah A., Miller, Edward J., Liesa, Marc, Shirihai, Orian S, Pimentel, David R., Cohen, Richard A., Colucci, Wilson S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268348/
https://ncbi.nlm.nih.gov/pubmed/25109264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.07.018
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