High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II

BACKGROUND: Diet-induced obesity leads to metabolic heart disease (MHD) characterized by increased oxidative stress that may cause oxidative post-translational modifications (OPTM) of cardiac mitochondrial proteins. The functional consequences of OPTM of cardiac mitochondrial proteins in MHD are unk...

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Gepubliceerd in:J Mol Cell Cardiol
Hoofdauteurs: Sverdlov, Aaron L., Elezaby, Aly, Behring, Jessica B., Bachschmid, Markus M., Luptak, Ivan, Tu, Vivian H., Siwik, Deborah A., Miller, Edward J., Liesa, Marc, Shirihai, Orian S, Pimentel, David R., Cohen, Richard A., Colucci, Wilson S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268348/
https://ncbi.nlm.nih.gov/pubmed/25109264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.07.018
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