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2-Deoxy-D-Glucose Enhances Anesthethic Effects in Mice

BACKGROUND: The mechanisms of general anesthesia by volatile drugs remain largely unknown. Mitochondrial dysfunction and reduction in energy levels have been suggested to be associated with general anesthesia status. 2-Deoxy-d-glucose (2-DG), an analog of glucose, inhibits hexokinase and reduces cel...

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Bibliografiske detaljer
Udgivet i:Anesth Analg
Main Authors: Wang, Hui, Xu, Zhipeng, Wu, Anshi, Dong, Yuanlin, Zhang, Yiying, Yue, Yun, Xie, Zhongcong
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301982/
https://ncbi.nlm.nih.gov/pubmed/25390277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000520
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