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2-Deoxy-D-Glucose Attenuates Isoflurane-Induced Cytotoxicity in an In Vitro Cell Culture Model of H4 Human Neuroglioma Cells

BACKGROUND: β-amyloid protein (Aβ) accumulation and caspase activation have been shown to contribute to Alzheimer’s disease neuropathogenesis. Aβ is produced from amyloid precursor protein through proteolytic processing by aspartyl protease β-site APP-cleaving enzyme (BACE). The inhaled anesthetic i...

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Detalhes bibliográficos
Main Authors: Zhang, Jun, Dong, Yuanlin, Xu, Zhipeng, Zhang, Yiying, Pan, Chuxiong, McAuliffe, Sayre, Ichinose, Fumito, Yue, Yun, Liang, Weimin, Xie, Zhongcong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224184/
https://ncbi.nlm.nih.gov/pubmed/21965367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31822e913c
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