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Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness.

NCTC 2071 cells are unable to synthesize the monosialoganglioside GM1. When grown in chemically defined medium these cells contained no detectable GM1 and did not accumulate 3': 5'-cyclic AMP in response to choleragen. Incubation of the cells with [3H]GM1 permitted quantification of ganglioside upta...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Moss, J, Fishman, P H, Manganiello, V C, Vaughan, M, Brady, R O
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1976
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/177969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.4.1034
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