Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen.

Choleragen and its A protomer catalyzed the hydrolysis of NAD to ADP-ribose and nicotinamide. NADase activity was inhibited by gangliosides GM1 (galactosyl-N-acetylgalactosaminyl-[N-acetylneuraminyl]-galactosylglucosylceramide), GM2 (N-acetylgalactosaminyl-[N-acetylneuraminyl]-galactosylglucosylcera...

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Detalhes bibliográficos
Main Authors: Moss, J, Osborne, J C, Fishman, P H, Brewer, H B, Vaughan, M, Brady, R O
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC393199/
https://ncbi.nlm.nih.gov/pubmed/13371
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