Preclinical Trials for Prevention of Tumor Progression of Hepatocellular Carcinoma by LZ-8 Targeting c-Met Dependent and Independent Pathways

Hepatocellular carcinoma (HCC) is among the most lethal cancers. Mounting studies highlighted the essential role of the HGF/c-MET axis in driving HCC tumor progression. Therefore, c-Met is a potential therapeutic target for HCC. However, several concerns remain unresolved in c-Met targeting. First,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Jia-Ru, Hu, Chi-Tan, You, Ren-In, Ma, Pei-Ling, Pan, Siou-Mei, Lee, Ming-Che, Wu, Wen-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301873/
https://ncbi.nlm.nih.gov/pubmed/25607934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114495
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