Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2

Hepatocyte growth factor (HGF) and its receptor c-Met were frequently deregulated in hepatocellular carcinoma (HCC). Signaling pathways activated by HGF-c-Met are promising targets for preventing HCC progression. HGF can induce the reactive oxygen species (ROS) signaling for cell adhesion, migration...

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Udgivet i:Oncotarget
Main Authors: Lin, Chung-Yi, Hu, Chi-Tan, Cheng, Chuan-Chu, Lee, Ming-Che, Pan, Siou-Mei, Lin, Teng-Yi, Wu, Wen-Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905458/
https://ncbi.nlm.nih.gov/pubmed/26840563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7093
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