Functional Comparison of Induced Pluripotent Stem Cell- and Blood-Derived GPIIbIIIa Deficient Platelets

Human induced pluripotent stem cells (hiPSCs) represent a versatile tool to model genetic diseases and are a potential source for cell transfusion therapies. However, it remains elusive to which extent patient-specific hiPSC-derived cells functionally resemble their native counterparts. Here, we gen...

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Bibliographic Details
Published in:PLoS One
Main Authors: Orban, Mathias, Goedel, Alexander, Haas, Jessica, Sandrock-Lang, Kirstin, Gärtner, Florian, Jung, Christian Billy, Zieger, Barbara, Parrotta, Elvira, Kurnik, Karin, Sinnecker, Daniel, Wanner, Gerhard, Laugwitz, Karl-Ludwig, Massberg, Steffen, Moretti, Alessandra
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301811/
https://ncbi.nlm.nih.gov/pubmed/25607928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115978
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