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Both High-Fidelity Replicative and Low-Fidelity Y-Family Polymerases Are Involved in DNA Rereplication

DNA rereplication is a major form of aberrant replication that causes genomic instabilities, such as gene amplification. However, little is known about which DNA polymerases are involved in the process. Here, we report that low-fidelity Y-family polymerases (Y-Pols), Pol η, Pol ι, Pol κ, and REV1, s...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Sekimoto, Takayuki, Oda, Tsukasa, Kurashima, Kiminori, Hanaoka, Fumio, Yamashita, Takayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301717/
https://ncbi.nlm.nih.gov/pubmed/25487575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01153-14
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