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Activation of PPARδ: from computer modelling to biological effects
PPARδ is a ligand-activated receptor that dimerizes with another nuclear receptor of the retinoic acid receptor family. The dimers interact with other co-activator proteins and form active complexes that bind to PPAR response elements and promote transcription of genes involved in lipid metabolism....
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| Published in: | Br J Pharmacol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BlackWell Publishing Ltd
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301687/ https://ncbi.nlm.nih.gov/pubmed/25255770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12950 |
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