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The promise and perils of HDAC inhibitors in neurodegeneration

Histone deacetylases (HDACs) represent emerging therapeutic targets in the context of neurodegeneration. Indeed, pharmacologic inhibition of HDACs activity in the nervous system has shown beneficial effects in several preclinical models of neurological disorders. However, the translation of such the...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Didonna, Alessandro, Opal, Puneet
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301678/
https://ncbi.nlm.nih.gov/pubmed/25642438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.147
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