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HDAC inhibitors and neurodegeneration: at the edge between protection and damage

The use of histone deacetylase inhibitors (HDACIs) as a therapeutic tool for neurodegenerative disorders has been examined with great interest in the last decade. The functional response to treatment with broad-spectrum inhibitors however, has been heterogeneous: protective in some cases and detrime...

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Detalhes bibliográficos
Main Authors: Dietz, Karen C., Casaccia, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871984/
https://ncbi.nlm.nih.gov/pubmed/20123018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.01.011
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