Genetic diversity is a predictor of mortality in humans

BACKGROUND: It has been well-established, both by population genetics theory and direct observation in many organisms, that increased genetic diversity provides a survival advantage. However, given the limitations of both sample size and genome-wide metrics, this hypothesis has not been comprehensiv...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Bihlmeyer, Nathan A, Brody, Jennifer A, Smith, Albert Vernon, Lunetta, Kathryn L, Nalls, Mike, Smith, Jennifer A, Tanaka, Toshiko, Davies, Gail, Yu, Lei, Mirza, Saira Saeed, Teumer, Alexander, Coresh, Josef, Pankow, James S, Franceschini, Nora, Scaria, Anish, Oshima, Junko, Psaty, Bruce M, Gudnason, Vilmundur, Eiriksdottir, Gudny, Harris, Tamara B, Li, Hanyue, Karasik, David, Kiel, Douglas P, Garcia, Melissa, Liu, Yongmei, Faul, Jessica D, Kardia, Sharon LR, Zhao, Wei, Ferrucci, Luigi, Allerhand, Michael, Liewald, David C, Redmond, Paul, Starr, John M, De Jager, Philip L, Evans, Denis A, Direk, Nese, Ikram, Mohammed Arfan, Uitterlinden, André, Homuth, Georg, Lorbeer, Roberto, Grabe, Hans J, Launer, Lenore, Murabito, Joanne M, Singleton, Andrew B, Weir, David R, Bandinelli, Stefania, Deary, Ian J, Bennett, David A, Tiemeier, Henning, Kocher, Thomas, Lumley, Thomas, Arking, Dan E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301661/
https://ncbi.nlm.nih.gov/pubmed/25543667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-014-0159-7
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