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ccm2-like is required for cardiovascular development as a novel component of the Heg-CCM pathway

The Heart of Glass-Cerebral Cavernous Malformation (Heg-CCM) pathway is essential for normal cardiovascular development in zebrafish and mouse. In zebrafish, the Heg-CCM pathway mutants santa(ccm1/san), valentine (ccm2/vtn), and heart of glass (heg) exhibit severely dilated hearts and inflow tracts...

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Détails bibliographiques
Publié dans:Dev Biol
Auteurs principaux: Rosen, Jonathan N., Sogah, Vanessa M., Ye, Lillian Y., Mably, John D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301579/
https://ncbi.nlm.nih.gov/pubmed/23328253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.01.006
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