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Activation of the intrinsic apoptosis pathway contributes to the induction of apoptosis in hepatocellular carcinoma cells by valproic acid

The level of histone deacetylation is closely associated with the genesis and development of tumors, but the antitumor effect and mechanism of the class I histone deacetylase inhibitor (HDACI) valproate acid sodium (VPA) on hepatocellular carcinoma cells has not been clearly demonstrated. In the pre...

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Publicat a:Oncol Lett
Autors principals: YANG, WEIHUA, ZHAO, XIA, PEI, FENGYAN, JI, MINGYU, MA, WANSHAN, WANG, YUNSHAN, JIANG, GUOSHENG
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301473/
https://ncbi.nlm.nih.gov/pubmed/25621063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2739
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