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Apoptosis Induction by 13-Acetoxyrolandrolide through the Mitochondrial Intrinsic Pathway

The aim of this study was to evaluate the mechanisms of cytotoxicity of the sesquiterpene lactone 13-acetoxyrolandrolide, an NF-κB inhibitor that was previously isolated from Rolandra fruticosa. The effects associated with inhibition of the NFκB pathway included dose-dependent inhibition of the NF-κ...

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Detalhes bibliográficos
Main Authors: Acuña, Ulyana Muñoz, Matthew, Susan, Pan, Li, Kinghorn, A. Douglas, Swanson, Steven M., Carcache de Blanco, Esperanza J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055509/
https://ncbi.nlm.nih.gov/pubmed/24338805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ptr.5091
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