CD4 T cells specific for a latency-associated γ-herpesvirus epitope are polyfunctional and cytotoxic()

The oncogenic γ-herpesviruses EBV and KSHV are ubiquitous human pathogens that establish lifelong latent infections maintained by intermittent viral reactivation and reinfection. Effector CD4 T cells are critical for control of viral latency and in immune therapies for virus-associated tumors. Here...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Freeman, Michael L., Burkum, Claire E., Cookenham, Tres, Roberts, Alan D., Lanzer, Kathleen G., Huston, Gail E., Jensen, Meghan K., Sidney, John, Peters, Bjoern, Kohlmeier, Jacob E., Woodland, David L., van Dyk, Linda F., Sette, Alessandro, Blackman, Marcia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301266/
https://ncbi.nlm.nih.gov/pubmed/25378595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302060
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