The Sheep Tetherin Paralog oBST2B Blocks Envelope Glycoprotein Incorporation into Nascent Retroviral Virions

Bone marrow stromal cell antigen 2 (BST2) is a cellular restriction factor with a broad antiviral activity. In sheep, the BST2 gene is duplicated into two paralogs termed oBST2A and oBST2B. oBST2A impedes viral exit of the Jaagsiekte sheep retroviruses (JSRV), most probably by retaining virions at t...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Murphy, Lita, Varela, Mariana, Desloire, Sophie, Ftaich, Najate, Murgia, Claudio, Golder, Matthew, Neil, Stuart, Spencer, Thomas E., Wootton, Sarah K., Lavillette, Dimitri, Terzian, Christophe, Palmarini, Massimo, Arnaud, Frédérick
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301133/
https://ncbi.nlm.nih.gov/pubmed/25339764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02751-14
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