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Immunoelectron Microscopic Evidence for Tetherin/BST2 as the Physical Bridge between HIV-1 Virions and the Plasma Membrane

Tetherin/BST2 was identified in 2008 as the cellular factor responsible for restricting HIV-1 replication at a very late stage in the lifecycle. Tetherin acts to retain virion particles on the plasma membrane after budding has been completed. Infected cells that express large amounts of tetherin dis...

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Autores principales: Hammonds, Jason, Wang, Jaang-Jiun, Yi, Hong, Spearman, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816691/
https://ncbi.nlm.nih.gov/pubmed/20140192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000749
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