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Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.

Hepatocytes are extensively used in studies of gene regulation but cannot be maintained in long-term culture as replicating, differentiated cells while remaining nontumorigenic. We have derived two hepatocyte lines from livers of transgenic mice overexpressing transforming growth factor alpha, a pot...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wu, J C, Merlino, G, Fausto, N
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1994
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7904757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.2.674
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