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Inactivation of Multiple Bacterial Histidine Kinases by Targeting the ATP-Binding Domain

[Image: see text] Antibacterial agents that exploit new targets will be required to combat the perpetual rise of bacterial resistance to current antibiotics. We are exploring the inhibition of histidine kinases, constituents of two-component systems. Two-component systems are the primary signaling p...

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Publié dans:ACS Chem Biol
Auteurs principaux: Wilke, Kaelyn E., Francis, Samson, Carlson, Erin E.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301073/
https://ncbi.nlm.nih.gov/pubmed/25531939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5008019
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