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Inactivation of Multiple Bacterial Histidine Kinases by Targeting the ATP-Binding Domain

[Image: see text] Antibacterial agents that exploit new targets will be required to combat the perpetual rise of bacterial resistance to current antibiotics. We are exploring the inhibition of histidine kinases, constituents of two-component systems. Two-component systems are the primary signaling p...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Wilke, Kaelyn E., Francis, Samson, Carlson, Erin E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301073/
https://ncbi.nlm.nih.gov/pubmed/25531939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5008019
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