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Activity-Based Probe for Histidine Kinase Signaling

Bacterial two-component systems (TCSs) are signaling pathways composed of two proteins, a histidine kinase (HK) and a response regulator (RR). Upon stimulation, the HK autophosphorylates at a conserved histidine. The phosphoryl group is subsequently transferred to an aspartate on a RR, eliciting an...

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Detalhes bibliográficos
Main Authors: Wilke, Kaelyn E., Francis, Samson, Carlson, Erin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415608/
https://ncbi.nlm.nih.gov/pubmed/22606938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3041702
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