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Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases

[Image: see text] JmjC-domain containing histone demethylases (JHDMs) play critical roles in many key cellular processes and have been implicated in multiple disease conditions. Each enzyme within this family is known to have a strict substrate scope, specifically the position of the lysine within t...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Marholz, Laura J., Chang, Le, Old, William M., Wang, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301071/
https://ncbi.nlm.nih.gov/pubmed/25335116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5006867
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