Efflux-mediated fluoroquinolone resistance in the multidrug-resistant Pseudomonas aeruginosa clinical isolate PA7: identification of a novel MexS variant involved in upregulation of the mexEF-oprN multidrug efflux operon

The emergence of multidrug-resistant Pseudomonas aeruginosa has become a serious problem in medical settings. P. aeruginosa clinical isolate PA7 is resistant to fluoroquinolones, aminoglycosides, and most β-lactams but not imipenem. In this study, enhanced efflux-mediated fluoroquinolone resistance...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Principais autores: Morita, Yuji, Tomida, Junko, Kawamura, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301020/
https://ncbi.nlm.nih.gov/pubmed/25653649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00008
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