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Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation

Neuronal death induced by overactivation of N-methyl-d-aspartate receptors (NMDARs) is implicated in the pathophysiology of many neurodegenerative diseases such as stroke, epilepsy and traumatic brain injury. This toxic effect is mainly mediated by NR2B-containing extrasynaptic NMDARs, while NR2A-co...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Lauro, Clotilde, Catalano, Myriam, Di Paolo, Eleonora, Chece, Giuseppina, de Costanzo, Ida, Trettel, Flavia, Limatola, Cristina
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301004/
https://ncbi.nlm.nih.gov/pubmed/25653593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00472
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