Adenosine A(1) Receptors and Microglial Cells Mediate CX3CL1-Induced Protection of Hippocampal Neurons Against Glu-Induced Death

Fractalkine/CX3CL1 is a neuron-associated chemokine, which modulates microglia-induced neurotoxicity activating the specific and unique receptor CX3CR1. CX3CL1/CX3CR1 interaction modulates the release of cytokines from microglia, reducing the level of tumor necrosis factor-α, interleukin-1-β, and ni...

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Dettagli Bibliografici
Autori principali: Lauro, Clotilde, Cipriani, Raffaela, Catalano, Myriam, Trettel, Flavia, Chece, Giuseppina, Brusadin, Valentina, Antonilli, Letizia, van Rooijen, Nico, Eusebi, Fabrizio, Fredholm, Bertil B, Limatola, Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055460/
https://ncbi.nlm.nih.gov/pubmed/20200508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.26
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