Efficient Reverse Genetics Reveals Genetic Determinants of Budding and Fusogenic Differences between Nipah and Hendra Viruses and Enables Real-Time Monitoring of Viral Spread in Small Animal Models of Henipavirus Infection

Nipah virus (NiV) and Hendra virus (HeV) are closely related henipaviruses of the Paramyxovirinae. Spillover from their fruit bat reservoirs can cause severe disease in humans and livestock. Despite their high sequence similarity, NiV and HeV exhibit apparent differences in receptor and tissue tropi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yun, Tatyana, Park, Arnold, Hill, Terence E., Pernet, Olivier, Beaty, Shannon M., Juelich, Terry L., Smith, Jennifer K., Zhang, Lihong, Wang, Yao E., Vigant, Frederic, Gao, Junling, Wu, Ping, Lee, Benhur, Freiberg, Alexander N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300668/
https://ncbi.nlm.nih.gov/pubmed/25392218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02583-14
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