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Electron Cryotomography Studies of Maturing HIV-1 Particles Reveal the Assembly Pathway of the Viral Core

To better characterize the assembly of the HIV-1 core, we have used electron cryotomography (ECT) to image infected cells and the viral particles cryopreserved next to them. We observed progressive stages of virus assembly and egress, including flower-like flat Gag lattice assemblies, hemispherical...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Woodward, Cora L., Cheng, Sarah N., Jensen, Grant J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300640/
https://ncbi.nlm.nih.gov/pubmed/25392219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02997-14
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